Studies on the chemical constituents of the vines of Streptocaulon juventas (Lour.) Merr.

›› 2008, Vol. 3 ›› Issue (5): 193-198.

Studies on the chemical constituents of the vines of Streptocaulon juventas (Lour.) Merr.

收稿日期:2008-06-10 修回日期:2008-10-15 出版日期:2008-10-15 发布日期:2008-10-15

Studies on the chemical constituents of the vines of Streptocaulon juventas (Lour.) Merr.

Zhihui Liu; Songbo Li; Na Han; Dongxue Sun; Yunfeng Cao; Jun Yin *

School of Traditional Chinese Meteria Medica, Shenyang Pharmaceutical University, Shenyang

Received:2008-06-10 Revised:2008-10-15 Online:2008-10-15 Published:2008-10-15
Contact: Jun Yin

摘要/Abstract

Abstract: The aqueous extract of the vines of Streptocaulon juventas was divided into four fractions following adsorption resin chromatography. Among them, the 30% fraction exhibited the strongest antiproliferate activity against human HL-60 leukemia cell lines. The chemical constituents of this fraction were investigated. Nine compounds were isolated by column chromatography and recrystallization. Their structures were identified as syringaldehyde (1), isofraxidin (2), ferulic acid (3), β -sitosterol (4), scopoletin (5), syringic acid (6), salicylaldehyde (7), scoparone (8), and daucosterol (9). Except for β-sitosterol and daucosterol, the other compounds were obtained from the genus for the first time.

Key words: Streptocaulon juventas, Asclepiadaceae, human HL-60 leukemia cell line, vines

. Studies on the chemical constituents of the vines of Streptocaulon juventas (Lour.) Merr.[J]. , 2008, 3(5): 193-198.

Zhihui Liu;Songbo Li;Na Han;Dongxue Sun;Yunfeng Cao;Jun Yin *. Studies on the chemical constituents of the vines of Streptocaulon juventas (Lour.) Merr.[J]. , 2008, 3(5): 193-198.

亚洲传统医药

Studies on the chemical constituents of the vines of Streptocaulon juventas (Lour.) Merr.

Studies on the chemical constituents of the vines of Streptocaulon juventas (Lour.) Merr.

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