›› 2012, Vol. 7 ›› Issue (5): 226-235.

• Regular Articles • 上一篇    下一篇

Pharmacognostical studies of the root of Capparis sepiaria L. (Himsra) - an ayurvedic drug

Varadharajan Madhavan 1
, Sunkam Yoganarasimhan 1*, Magadi Gurudeva 2,
Ajay Shankar Pandey 1, Deveswaran Rajamanickam 3   

  1. 1 Department of Pharmacognosy, MS Ramaiah College of Pharmacy, Bangalore 560 054, Karnataka, India; 2 Department of Botany, VV Pura College of Science, Bangalore 560 004, Karnataka, India; 3 Department of Pharmaceutics, MS Ramaiah College of Pharmacy, Bangalore 560 054, Karnataka, India
  • 收稿日期:2012-05-02 修回日期:2012-10-12 出版日期:2012-10-20 发布日期:2012-10-20

Pharmacognostical studies of the root of Capparis sepiaria L. (Himsra) - an ayurvedic drug

Varadharajan Madhavan 1
, Sunkam Yoganarasimhan 1*, Magadi Gurudeva 2,
Ajay Shankar Pandey 1, Deveswaran Rajamanickam 3   

  1. 1 Department of Pharmacognosy, MS Ramaiah College of Pharmacy, Bangalore 560 054, Karnataka, India; 2 Department of Botany, VV Pura College of Science, Bangalore 560 004, Karnataka, India; 3 Department of Pharmaceutics, MS Ramaiah College of Pharmacy, Bangalore 560 054, Karnataka, India
  • Received:2012-05-02 Revised:2012-10-12 Online:2012-10-20 Published:2012-10-20

摘要: Capparis sepiaria is known as Himsra in ayurvedic medicine and is used in the treatment of several diseases. The
pharmacognostical evaluation of the root of C. sepiaria which is used for medicinal purposes is presented in this paper. The study
includes the morphology of the plant, macro-, microscopical characteristics of the root, macerate elements, histochemical and
UVstudies, physico-chemical constants and phytochemical analysis. The findings revealed the presence of druse-type crystals in
cork cells, the presence of stone cells in many layers in the secondary cortex, the presence of abundant simple starch grains in
the secondary cortex and in medullary ray cells, and the presence of a pericyclic stone cell layer which helps the identification
of the drug. Preliminary phytochemical analysis revealed the presence of alkaloids, carbohydrates, phytosterols and flavonoids
in the alcoholic extract while the aqueous extract contained alkaloids, carbohydrates, saponins, flavonoids, gums and mucilage.
The petroleum ether extract contained phytosterols, fixed oils and fats. HPTLC finger print profiles of the aqueous and alcoholic
extracts have been obtained which will be useful for the standardization of this drug and also help to isolate biomarker
compounds.

Abstract: Capparis sepiaria is known as Himsra in ayurvedic medicine and is used in the treatment of several diseases. The
pharmacognostical evaluation of the root of C. sepiaria which is used for medicinal purposes is presented in this paper. The study
includes the morphology of the plant, macro-, microscopical characteristics of the root, macerate elements, histochemical and
UVstudies, physico-chemical constants and phytochemical analysis. The findings revealed the presence of druse-type crystals in
cork cells, the presence of stone cells in many layers in the secondary cortex, the presence of abundant simple starch grains in
the secondary cortex and in medullary ray cells, and the presence of a pericyclic stone cell layer which helps the identification
of the drug. Preliminary phytochemical analysis revealed the presence of alkaloids, carbohydrates, phytosterols and flavonoids
in the alcoholic extract while the aqueous extract contained alkaloids, carbohydrates, saponins, flavonoids, gums and mucilage.
The petroleum ether extract contained phytosterols, fixed oils and fats. HPTLC finger print profiles of the aqueous and alcoholic
extracts have been obtained which will be useful for the standardization of this drug and also help to isolate biomarker
compounds.

Key words: Capparis sepiaria, root, pharmacognosy, hptlc studies, himsra