亚洲传统医药
亚洲传统医药

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›› 2015, Vol. 10 ›› Issue (6): 134-139.

• 论文 • 上一篇    下一篇

Berberine: New perspectives for old TraditionalChinese Medicine

Feng Xu 1,2, Yu Chen 2, Meng Wang 1, Wei Xu 2*, Feng Qiu 1*   

  1. 1 School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical UniVersity,Shenyang, 110016, China;2 School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang110016, China
  • 收稿日期:2015-04-20 修回日期:2015-10-19 出版日期:2015-12-20 发布日期:2015-12-20

Berberine: New perspectives for old TraditionalChinese Medicine

Feng Xu 1,2, Yu Chen 2, Meng Wang 1, Wei Xu 2*, Feng Qiu 1*   

  1. 1 School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical UniVersity,Shenyang, 110016, China;2 School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang110016, China
  • Received:2015-04-20 Revised:2015-10-19 Online:2015-12-20 Published:2015-12-20
  • Contact: Wei Xu*, Feng Qiu*

摘要： Traditional Chinese medicines have been used since the origin of human beings to counteract a number of diseases. Among these
plant derivatives, berberine, which is probably the most widely distributed, possesses a broad range of therapeutic uses as a
promising anticancer leading compound. Recently, more and more reports support the evidence that berberine has anticancer
effects, being able to block the proliferation of or to kill cancer cells. This review will focus on an extensive analysis of berberine
chemical properties, molecular target and the application in cancer in order to provide new directions in the future research.

Abstract: Traditional Chinese medicines have been used since the origin of human beings to counteract a number of diseases. Among these
plant derivatives, berberine, which is probably the most widely distributed, possesses a broad range of therapeutic uses as a
promising anticancer leading compound. Recently, more and more reports support the evidence that berberine has anticancer
effects, being able to block the proliferation of or to kill cancer cells. This review will focus on an extensive analysis of berberine
chemical properties, molecular target and the application in cancer in order to provide new directions in the future research.

Key words: berberine, molecular target, cancer, traditional medicine

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