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Microbiological assay of a Mixture of Three Lactic acid Bacteria Metabolites

Xintong Niu 1, Tianfei Long 1, Yu Chen 2*   

  1. 1 Guangzhou Longmuliangcao Biological Technology Co., Ltd., Guangzhou 511400, China; 2 School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China
  • 收稿日期:2016-09-19 修回日期:2016-11-02 出版日期:2016-12-20 发布日期:2016-11-02

Microbiological assay of a Mixture of Three Lactic acid Bacteria Metabolites

Xintong Niu 1, Tianfei Long 1, Yu Chen 2*   

  1. 1 Guangzhou Longmuliangcao Biological Technology Co., Ltd., Guangzhou 511400, China; 2 School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2016-09-19 Revised:2016-11-02 Online:2016-12-20 Published:2016-11-02
  • Contact: Yu Chen *, School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China; Tel: +86-24-23986409; E-mail: gzweishengwu@126.com.

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摘要： Recently, antibiotic resistant microorganisms have become an increasing public health problem. Traditional Chinese medicine and probiotic treatment have recently received much attention as alternative therapeutic methods. In order to investigate the germicidal efficacy of a mixture of three lactic acid bacteria metabolites, we carried out a study involving a cylinder-plate assay and a carrier quantitative germicidal test. It was noted that the mixture of three lactic acid bacteria metabolites showed an excellent antimicrobial effect on Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 25922, Canidia albicans ATCC 10231, and Aspergillius niger ATCC 16404. Our findings provide an experimental basis for future investigation of their practical application in combination with traditional Chinese medicines.

关键词: Probiotics, cylinder-plate assay, carrier quantitative germicidal test

Abstract: Recently, antibiotic resistant microorganisms have become an increasing public health problem. Traditional Chinese medicine and probiotic treatment have recently received much attention as alternative therapeutic methods. In order to investigate the germicidal efficacy of a mixture of three lactic acid bacteria metabolites, we carried out a study involving a cylinder-plate assay and a carrier quantitative germicidal test. It was noted that the mixture of three lactic acid bacteria metabolites showed an excellent antimicrobial effect on Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 25922, Canidia albicans ATCC 10231, and Aspergillius niger ATCC 16404. Our findings provide an experimental basis for future investigation of their practical application in combination with traditional Chinese medicines.

Key words: Probiotics, cylinder-plate assay, carrier quantitative germicidal test

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