A review on chemical constituents and bioactivities of
Viburnum odoratissimum

亚洲传统医药 ›› 2020, Vol. 15 ›› Issue (5): 263-287.

A review on chemical constituents and bioactivities of Viburnum odoratissimum

Xiaobian Xue 1, Guodong Yao 1,2*

1 Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; 2 Jiangsu Kanion Pharmaceutical Company Ltd., Lianyungang 222001, China

收稿日期:2020-05-20 修回日期:2020-08-06 接受日期:2020-08-06 出版日期:2020-10-20 发布日期:2020-10-30

A review on chemical constituents and bioactivities of Viburnum odoratissimum

Xiaobian Xue 1, Guodong Yao 1,2*

1 Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; 2 Jiangsu Kanion Pharmaceutical Company Ltd., Lianyungang 222001, China

Received:2020-05-20 Revised:2020-08-06 Accepted:2020-08-06 Online:2020-10-20 Published:2020-10-30
Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-23986510; E-mail: guodong_yao@163.com. E-mail:guodong_yao@163.com

摘要/Abstract

摘要： Viburnum odoratissimum belongs to viburnum genus of the Caprifoliaceae family. Previous studies reported many chemical constituents in this plant, including monoterpenoids, sesquiterpenoids, vibsane-type diterpenes, triterpenes, coumarins, and lignans, and various pharmacological bioactivities the extracts of V. odoratissimum such as anti-tumor, neuroprotective, antiinflammatory, ichthyism and anti-oxidant activity. Besides, the total synthesis of vibsane-type diterpenes and their derivatives have attracted considerable attention because of their wide-ranging anti-tumor activity. This present study not only systematically summarizes the compounds isolated from V. odoratissimum, and the structure-activity relationship of these compounds.

关键词: Viburnum odoratissimum, compound structures, vibsane-type diterpenes, pharmacological effects

Abstract: Viburnum odoratissimum belongs to viburnum genus of the Caprifoliaceae family. Previous studies reported many chemical constituents in this plant, including monoterpenoids, sesquiterpenoids, vibsane-type diterpenes, triterpenes, coumarins, and lignans, and various pharmacological bioactivities the extracts of V. odoratissimum such as anti-tumor, neuroprotective, antiinflammatory, ichthyism and anti-oxidant activity. Besides, the total synthesis of vibsane-type diterpenes and their derivatives have attracted considerable attention because of their wide-ranging anti-tumor activity. This present study not only systematically summarizes the compounds isolated from V. odoratissimum, and the structure-activity relationship of these compounds.

Key words: Viburnum odoratissimum, compound structures, vibsane-type diterpenes, pharmacological effects

Xiaobian Xue, Guodong Yao. A review on chemical constituents and bioactivities of Viburnum odoratissimum[J]. 亚洲传统医药, 2020, 15(5): 263-287.

Xiaobian Xue, Guodong Yao. A review on chemical constituents and bioactivities of Viburnum odoratissimum[J]. Asian Journal of Traditional Medicines, 2020, 15(5): 263-287.

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A review on chemical constituents and bioactivities of Viburnum odoratissimum

A review on chemical constituents and bioactivities of Viburnum odoratissimum

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