亚洲传统医药

本期目录

2023年, 第18卷, 第4期　刊出日期：2023-08-30 上一期   

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Evaluation of the effect of shodhana (detoxification) process using chromatographic profiling (HPTLC, HPLC, LC-MS, and GC-MS) and estimation of the content of toxic colchicine in Gloriosa superba Linn. tubers Ajay Kumar Meena, Poorna Venktaraman, Mohit Motiwale, Ravindra Singh, Kusuma Ganji, N. Srikanth, K. S. Dhiman 2023 (4):  143-162.  摘要 ( 159 )   PDF(6977KB) ( 105 )   Shodhana (purification/detoxification) is an important aspect of Ayurveda. It has been described in several important pieces of literature. In this study, we performed shodhana process on Langali (Gloriosa superba Linn.) tubers of family Liliaceae, a semi-woody herbaceous climber with significant therapeutic properties. We compared the unprocessed (before purification) and processed (after purification) samples based on the phytochemical, physicochemical, and chromatographic study, including HPTLC, HPLC, GC-MS and LC-MS. Significant changes were observed in profiling after the shodhana process. This plant contains colchicine, known for its toxic effects, particularly cardiotoxicity. Therefore, we quantified colchicine in the unprocessed and processed samples of Gloriosa superba Linn. tubers using HPLC method. Results showed that the percentage of colchicine was reduced by 13.67% in chloroform extract and 20.97% in ethanol extracts after the shodhana process. 相关文章 | 计量指标

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Application of Caenorhabditis elegans in screening active ingredients of traditional Chinese medicine Ling Zhao, Mengyue Zhang, Yingying Wu, Rutian Jin, Lingxuan Li, Ying Long, Xin Wu 2023 (4):  163-172.  摘要 ( 157 )   PDF(1898KB) ( 176 )   People continue to recognize the important role of Chinese medicine in the treatment of diseases, and there is an urgent need to clarify the mechanism of Chinese medicine. Because of the multi-target and multi-component characteristics of traditional Chinese medicine, it is difficult to elaborate from a single perspective. As a high-quality animal model, Caenorhabditis elegans with the characteristics of small size and fast reproduction, has been widely used in traditional Chinese medicine activity experiments. In this article, Caenorhabditis elegans, as model organisms used to screen the active components of traditional Chinese medicine were reviewed. 相关文章 | 计量指标

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Chemical composition and biological activities of Portulaca oleracea Haonan Yu, Yi’an Shi, Yibo Wang, Yunpeng Yang, Ying Li, Yu Chen 2023 (4):  173-202.  摘要 ( 158 )   PDF(1051KB) ( 76 )   Portulaca oleracea (P. oleracea) is a traditional Chinese herbal that has the effects of soothing the liver and clearing collaterals, strengthening the spleen and stomach, moistening the intestines and detoxifying. With the development of the pharmaceutical industry, the medicinal value of P. oleracea is becoming increasingly prominent. It is commonly used in clinical practice for clearing heat and detoxifying, inhibiting bacteria, preventing and treating diseases such as hypertension, coronary heart disease, and cerebral infarction, indicating its broad application prospects. This study reviews the chemical components and pharmacological activities of P. oleracea in recent decades. 相关文章 | 计量指标