亚洲传统医药

本期目录

2022年, 第17卷, 第3期　刊出日期：2022-06-23 上一期   

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Virtual screening of the active compounds and potential targets of Elephantopus tomentosus L. for the treatment of liver cancer based on a network pharmacology approach Wei Xu, Ming Bai, Xiaoxiao Huang 2022 (3):  85-93.  摘要 ( 235 )   PDF(1027KB) ( 274 )   Liver cancer is the leading cause of cancer-related death. As the clinical treatment for this disease is not satisfactory, it is urgent to discover new medications to treat liver cancer. Elephantopus tomentosus L. is a traditional whole grass herb, which contains sesquiterpene lactones, triterpenoids, aldehyde caffeic with good anti-tumor effect. In this study, molecular docking and network analysis were carried out to identify the active compounds, and predict the potential targets of E. tomentosus for the treatment of liver cancer. These attempts may provide insights for finding novel lead compounds for the treatment of liver cancer. 相关文章 | 计量指标

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Research review on the main chemical constituents and pharmacological effects of Tripterygium hypoglaucum (Levl.) Hutch. Yunfei Ai, Shuhui Dong, Xiaoxiao Huang, Shaojiang Song 2022 (3):  94-107.  摘要 ( 211 )   PDF(2350KB) ( 276 )   Tripterygium hypoglaucum (Levl.) Hutch. (THH), which belongs to Tripterygium genus of Celastraceae family, is widely used as the common Chinese herbal medicine. It has been reported that the chemical constituents of T. hypoglaucum include monoterpenoids, sesquiterpenoids, diterpenoids, triterpenoids, sesquiterpene alkaloids, flavonoids, anthraquinone derivatives, et al. These compounds showed a wide range of bioactivities, such as anti-inflammatory, anti-cancer, immunosuppressive, anti-HIV, anti-fertility and insecticidal activities. In this paper, we summarized the chemical constituents and pharmacological activities of T. hypoglaucum to provide a reference for its further research and developement. 相关文章 | 计量指标

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Chemical composition and pharmacological activities of Polygonum cuspidatum Yi’an Shi, Luming Pan, Jiayi Bi, Xuefei Yang, Jing Sun, Meng Zhang, Yu Chen 2022 (3):  108-115.  摘要 ( 221 )   PDF(902KB) ( 268 )   Polygonum cuspidatum is a traditional Chinese medicine, and its medicinal part is dry rhizome. It is mainly used to treat damp heat jaundice, burns, carbuncle, ulcer poisoning, amenorrhea, and snake bite. Recent studies have found that P. cuspidatum also contains active ingredients against coronaviruses. This paper reviews the chemical constituents and pharmacological activities of P. cuspidatum, so as to provide a scientific basis for the development and utilization of P. cuspidatum resources in the future. 相关文章 | 计量指标

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Research progress on the triterpenoids from the genus Schisandra and their biological activities Yongcheng Yang, Luqi Liu, Zijun Tang, Min Chen, Jingming Jia, Anhua Wang 2022 (3):  116-136.  摘要 ( 229 )   PDF(1520KB) ( 383 )   The plants of the genus Schisandra of the Schisandraceae family include the genus Schisandra and the genus Kadsura. In recent years, many kinds of triterpenoids have been isolated from the plants of genus Schisandra. Triterpenoids have attracted the attention of phytochemists and pharmacologists because they have novel skeletons and good anti-HIV, immunosuppressive and anti-tumor activities. This study provides an overview of the triterpenoids from the genus Schisandra and their biological activities. 相关文章 | 计量指标