Asian Journal of Traditional Medicines ›› 2019, Vol. 14 ›› Issue (4): 202-212.

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Research review on the main chemical constituents and pharmacological effects of Elephantopus scaber L.

Shuhui Dong, Ming Bai, Xiaoxiao Huang*, Shaojiang Song*   

  1. Department of Natural Products Chemistry, Key Laboratory of Computational ChemistryBased Natural Antitumor drug Research & Development, Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China
  • Received:2018-10-26 Accepted:2018-12-19 Online:2019-08-20 Published:2019-12-09
  • Contact: Address: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-23986510 (Xiaoxiao Huang); +86-24-23986510 (Shaojiang Song); E-mail: xiaoxiao270@163.com (Xiaoxiao Huang); songsj99@163.com (Shaojiang Song). E-mail:xiaoxiao270@163.com; songsj99@163.com

Abstract: Elephantopus scaber L. belongs to Elephantopus plant of Compositae, is widely used as the common Chinese herbal medicine in folk. Phytochemical investigations of the E. scaber have resulted in the isolation of triterpennoids, sesquiterpene lactones, sesquiterpene phenols, steroids, flavones, anthraquinones, peptides, lipid compounds and aryl compounds. It possesses the effects of antibacterial, clearing away heat and detoxification, detumescence and diuresis, and is used for treating lung cancer, cervical cancer, liver cancer, nasopharyngeal cancer, breast cancer, anemia and diarrhea. The research progress in the chemical constituents of E. scaber and pharmacological effects are reviewed for better explore and utilize the E. scaber resource.

Key words: Elephantopus scaber L., chemical compositions, pharmacological effects, research review