Asian Journal
Of Traditional Medicines

Abstract: The fruit peel of Calophyllum inophyllum is considered waste material from the production of oils from its fruit and is abundantly available in Vietnam. The preparation of extracts was carried out by the pressurized liquid extraction (PLE) method. The preliminary phytochemical screening revealed the presence of phenolic compounds. The antimicrobial studies of the methanolic and n-hexane extracts were carried out on standard micro-organisms, Staphylococcus aureus (ATCC 6538 P), Mycobacterium smegmatis (ATCC 14468), and Pseudomonas aeruginosa (ATCC 9027), using the disc diffusion method. The extracts demonstrated promising antibacterial activity against Staphylococcus aureus and Mycobacterium smegmatis. The presence of phenolic compounds was likely to be responsible for these activities.

Key words: Calophyllum inophyllum, fruit peel, phenolic compound, antimicrobial activity