A novel approach for quality control of Compound
Danshen Tablets by using Multi-wavelength highperformance
liquid chromatographic fingerprints and
chemometrics to predict the antioxidant activity

Asina Journal Of Traditional Medicines

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A novel approach for quality control of Compound Danshen Tablets by using Multi-wavelength highperformance liquid chromatographic fingerprints and chemometrics to predict the antioxidant activity

Jiao Chen, Guoxiang Sun*, Yue Yu

College of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, Liaoning 110016, China

Received:2017-09-06 Revised:2017-11-11 Online:2017-12-20 Published:2017-11-11
Contact: College of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, Liaoning 110016, China; E-mail: gxswmwys@163.com; Tel.: +86-24-23986286.

Abstract

Abstract: The objective of this paper was to establish an efficient method for quality control of Compound Danshen Tablets (CDST). A simple and reliable high-performance liquid chromatography (HPLC) method was developed both for multi-wavelength fusion fingerprint and quantitative determination. Off-line antioxidant assay was performed to predict the antioxidant activity of CDST using partial least squares (PLS) model. The present approach was powerful and reliable, which can be employed for comprehensively evaluate the quality consistency of traditional Chinese medicines (TCM).

Key words: antioxidant activity, Compound Danshen Tablets, content determination, multi-wavelength fusion fingerprint, Partial Least Squares

Jiao Chen, Guoxiang Sun, Yue Yu. A novel approach for quality control of Compound Danshen Tablets by using Multi-wavelength highperformance liquid chromatographic fingerprints and chemometrics to predict the antioxidant activity[J]. Asina Journal Of Traditional Medicines.

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Asian Journal
Of Traditional Medicines

A novel approach for quality control of Compound Danshen Tablets by using Multi-wavelength highperformance liquid chromatographic fingerprints and chemometrics to predict the antioxidant activity

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Asian Journal Of Traditional Medicines

A novel approach for quality control of Compound Danshen Tablets by using Multi-wavelength highperformance liquid chromatographic fingerprints and chemometrics to predict the antioxidant activity

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Asian Journal
Of Traditional Medicines