›› 2006, Vol. 1 ›› Issue (1): 7-10.

• 论文 • 上一篇    下一篇

Anti-tumor Constituents from Paris polyphylla

  

  • 收稿日期:2006-01-01 修回日期:2006-01-01 出版日期:2006-02-15 发布日期:2006-02-15

Anti-tumor Constituents from Paris polyphylla

Yu Wang 1; Wenyuan Gao 1*; Xinqiao Liu 1; Yutong Zuo 1; Haixia Chen1; and Hongquan
Duan 2   

  1. 1 The College of Pharmaceutical and Biotechnology, Tianjin University, Tianjin 300072, China; 2 The College of Pharmaceutical Science, Tianjin Medical University, Tianjin 300070, China.
  • Received:2006-01-01 Revised:2006-01-01 Online:2006-02-15 Published:2006-02-15
  • Contact: Wenyuan Gao

Abstract: To study the anti-tumor constituents from the rhizome of Paris polyphylla. The compounds were isolated
and purified by several chromatographic techniques and identified by chemicophysical properties and
spectral analyses. The anti-tumor experiment in vitro, the MTT method was applied to select active
constituents from Paris polyphalla. Eight compounds were obtained and identified as Falcarindiol (1),β
-ecdysterone (2), and six known saponins. Falcarindiol (1) was isolated from this plant for the first time, both
compounds 1 and 3-8 showed significant anti-tumor activities.

Key words: Paris polyphylla, falcarindiol, saponins, anti-tumor activity