亚洲传统医药
亚洲传统医药

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›› 2011, Vol. 6 ›› Issue (5): 224-230.

• Regular Articles • 上一篇    

Antimicrobial activity and reversal of dexamethasone depressed healing by roots of Ficus racemosa L.

  

  • 收稿日期:2011-09-15 修回日期:2011-10-30 出版日期:2011-10-20 发布日期:2011-10-20

Antimicrobial activity and reversal of dexamethasone depressed healing by roots of Ficus racemosa L.

Krishna Murti 1*, Upendra Kumar 2, Raghuvir Singh 3   

  1. 1. Department of Pharmacology, Singhania University, Jhunjhunu, Rajasthan 333515, India 2. Department of Pharmaceutical Chemistry, College of Pharmacy, Azamgarh, Uttar Pradesh 276136, India 3. Department of Pharmaceutics, PDM School of Pharmacy, Safidon, Jind, Haryana 126112, India
  • Received:2011-09-15 Revised:2011-10-30 Online:2011-10-20 Published:2011-10-20
  • Contact: Krishna Murti

Abstract: This study was conducted to evaluate aqueous & ethanolic extracts of Ficus racemosa for antibacterial and wound healing properties in presence of dexamethasone depressed healing conditions. Antibacterial properties of the extracts were studied against Klebsiella pneumoniae, Staphylococcus aureus and Escherichia coli bacterial strains, using the well diffusion method. Reversal mechanism of dexamethasone depressed wound healing properties by Ficus racemosa was determined using the incision and excision wound model. Extract of Ficus racemosa inhibited growth of all the test bacterial strains. Both the extract reverted the dexamethasone depressed healing effectively when compared with dexamethasone treated group. The results were comparatively significant (P< 0.05).

Key words: Ficus racemosa, wound healing, dexamethasone, antimicrobial activity, incision, excision wound model.

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