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Research progress on biotransformation of monoterpenes by Aspergillus niger

Siyu Hu, Peizhi Zou, Hongtao Yang, Dali Meng, Yu Chen*   

  1. School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China
  • 收稿日期:2017-04-16 修回日期:2017-10-11 出版日期:2017-12-20 发布日期:2017-10-11

Research progress on biotransformation of monoterpenes by Aspergillus niger

Siyu Hu, Peizhi Zou, Hongtao Yang, Dali Meng, Yu Chen*   

  1. School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2017-04-16 Revised:2017-10-11 Online:2017-12-20 Published:2017-10-11
  • Contact: School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China; Tel.: +86-24-23986409; E-mail:chenyu0208303@126.com.

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摘要： Aspergillus niger is a widespread aerobic fungus that has been used for many different biotransformation of natural products. Monoterpenes, commonly used in pharmaceutical products, are those containing two isoprene unit terpene molecules and molecular derivatives. They are widespread in higher plants secrete tissue, and show a variety of biological activities. In this review, we summarize a number of processes that have been developed for the transformation of monoterpenes by the cultures of Aspergillus niger, and these results could lay the foundation for identifying new drug leads in the future.

关键词: Aspergillus niger, monoterpenes, biotransformation

Abstract: Aspergillus niger is a widespread aerobic fungus that has been used for many different biotransformation of natural products. Monoterpenes, commonly used in pharmaceutical products, are those containing two isoprene unit terpene molecules and molecular derivatives. They are widespread in higher plants secrete tissue, and show a variety of biological activities. In this review, we summarize a number of processes that have been developed for the transformation of monoterpenes by the cultures of Aspergillus niger, and these results could lay the foundation for identifying new drug leads in the future.

Key words: Aspergillus niger, monoterpenes, biotransformation

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