亚洲传统医药

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Research review on the main chemical constituents and pharmacological effects of the samara derived from Ailanthus altissima (Mill.) Swingle

Peng Zhao 1, Zhiyang Yan 1, Rui Guo 1, Xiaoxiao Huang 1*   

  1. Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, PR China
  • 收稿日期:2017-11-13 修回日期:2017-12-19 出版日期:2018-06-20 发布日期:2017-12-19

Research review on the main chemical constituents and pharmacological effects of the samara derived from Ailanthus altissima (Mill.) Swingle

Peng Zhao 1, Zhiyang Yan 1, Rui Guo 1, Xiaoxiao Huang 1*   

  1. Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, PR China
  • Received:2017-11-13 Revised:2017-12-19 Online:2018-06-20 Published:2017-12-19
  • Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-23986510; E-mail: xiaoxiao270@163.com.

摘要: The samara of Ailanthus altissima (Mill.) Swingle., belonging to Ailanthus genus of Simaroubaceae family, is widely used as the common Chinese herbal medicine in folk. As a traditional medicinal agent, a wide spectrum of chemical constituents have been isolated from the samara, including steroids, triperpenoids, lignans, phenolic acids, quassioids, flavonoids and flavone glycosides. Its powder can be used as medicines for dysentery, metrorrhagia, ascariasis and hemostasis with astringents. The research shows that the samara has multiple activities and good development prospect, which has attracted a wide attention. Hence, this report is presented as a review centered on chemical constituents and pharmacological activities of the samara, aiming at its further development and potential as anticancer agents.

关键词: fruit of Ailanthus altissima (Mill.) Swingle, chemical constituents, pharmacological effects, review

Abstract: The samara of Ailanthus altissima (Mill.) Swingle., belonging to Ailanthus genus of Simaroubaceae family, is widely used as the common Chinese herbal medicine in folk. As a traditional medicinal agent, a wide spectrum of chemical constituents have been isolated from the samara, including steroids, triperpenoids, lignans, phenolic acids, quassioids, flavonoids and flavone glycosides. Its powder can be used as medicines for dysentery, metrorrhagia, ascariasis and hemostasis with astringents. The research shows that the samara has multiple activities and good development prospect, which has attracted a wide attention. Hence, this report is presented as a review centered on chemical constituents and pharmacological activities of the samara, aiming at its further development and potential as anticancer agents.

Key words: fruit of Ailanthus altissima (Mill.) Swingle, chemical constituents, pharmacological effects, review