亚洲传统医药

• Regular Article • 上一篇    下一篇

Antioxidant Activity of Pithecellobium clypearia (Jack) Benth dry branches and leaves

Han Zhang, Yuxi Wang, Ming Bai, Xiaoxiao Huang*   

  1. Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, PR China
  • 收稿日期:2017-11-29 修回日期:2018-01-24 出版日期:2018-08-20 发布日期:2018-01-24

Antioxidant Activity of Pithecellobium clypearia (Jack) Benth dry branches and leaves

Han Zhang, Yuxi Wang, Ming Bai, Xiaoxiao Huang*   

  1. Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, PR China
  • Received:2017-11-29 Revised:2018-01-24 Online:2018-08-20 Published:2018-01-24
  • Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-23986510 (Xiaoxiao Huang); E-mail: xiaoxiao270@163.com (Xiaoxiao Huang).

摘要: Several studies are going on worldwide directed towards finding natural antioxidants from plant origin. Literature reviews suggested that Pithecellobium clypearia shows strong free radical scavenging activity against various types of reactive oxygen species (ROS). Therefore, it is necessary to identify selective antioxidant agents from this plant. Phytochemical investigation of Pithecellobium clypearia led to the isolation of 20 known flavonoids. We studied in vitro antioxidant effect and free radical scavenging activity of these known flavonoids. The result showed that compared with the standard, compound 17 exhibited potent antioxidant activity in DPPH and ABTS radical scavenging assays. Moreover, the FRAP value of compound 13 displayed strong activity.

关键词: Pithecellobium clypearia, antioxidant activity, free radicals, ?avonoids

Abstract: Several studies are going on worldwide directed towards finding natural antioxidants from plant origin. Literature reviews suggested that Pithecellobium clypearia shows strong free radical scavenging activity against various types of reactive oxygen species (ROS). Therefore, it is necessary to identify selective antioxidant agents from this plant. Phytochemical investigation of Pithecellobium clypearia led to the isolation of 20 known flavonoids. We studied in vitro antioxidant effect and free radical scavenging activity of these known flavonoids. The result showed that compared with the standard, compound 17 exhibited potent antioxidant activity in DPPH and ABTS radical scavenging assays. Moreover, the FRAP value of compound 13 displayed strong activity.

Key words: Pithecellobium clypearia, antioxidant activity, free radicals, ?avonoids