Review: diterpenoids from Croton genus
(Euphorbiaceae) and their biological activity

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Review: diterpenoids from Croton genus (Euphorbiaceae) and their biological activity

Shaochun Shi, Han Zhang, Shuangshuang Li, Qingbo Liu*, Shaojiang Song*

Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, PR China

收稿日期:2018-10-15 修回日期:2018-12-05 出版日期:2018-12-20 发布日期:2018-12-05

Review: diterpenoids from Croton genus (Euphorbiaceae) and their biological activity

Shaochun Shi, Han Zhang, Shuangshuang Li, Qingbo Liu*, Shaojiang Song*

Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, PR China

Received:2018-10-15 Revised:2018-12-05 Online:2018-12-20 Published:2018-12-05
Contact: School of Traditional Chinese Materia Medica, Shenyang P0harmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-23986510 (Qingbo Liu), +86-24-23986510 (Shaojiang Song); E-mail: liuqingbolily@126.com (Qingbo Liu), songsj99@163.com (Shaojiang Song).

摘要/Abstract

摘要： The plants of Croton genus, belonging to Euphorbiaceae family, are widely used as herbal medicine in the folk. Popular uses include treatment of cancer, HIV, fever, hypertension, inflammation, intestinal worms, malaria, pain, ulcers and weight-loss. Diterpenoids are very common in Croton, corresponding to clerodanes, tiglianes, kauranes, labdanes, cembranes, halimanes, trachylobanes, crotofolanes and sarcopetalanes. There are numerous studies indicated that the main active chemical constituents of Croton were diterpenoids. The plants of Croton genus have been closely watched by researchers due to its multiple activities and good development prospect. To obtain a more comprehensive perspective, it is necessary to publish a review focusing on the “diterpenoids from the genus Croton”. This paper is presented as a review concentered on the diterpenoids different core frameworks and its pharmacological effects of Croton genus, which is useful to the further research and development of this plant.

关键词: Croton genus, diterpenoids, chemical constituents, pharmacological effects

Abstract: The plants of Croton genus, belonging to Euphorbiaceae family, are widely used as herbal medicine in the folk. Popular uses include treatment of cancer, HIV, fever, hypertension, inflammation, intestinal worms, malaria, pain, ulcers and weight-loss. Diterpenoids are very common in Croton, corresponding to clerodanes, tiglianes, kauranes, labdanes, cembranes, halimanes, trachylobanes, crotofolanes and sarcopetalanes. There are numerous studies indicated that the main active chemical constituents of Croton were diterpenoids. The plants of Croton genus have been closely watched by researchers due to its multiple activities and good development prospect. To obtain a more comprehensive perspective, it is necessary to publish a review focusing on the “diterpenoids from the genus Croton”. This paper is presented as a review concentered on the diterpenoids different core frameworks and its pharmacological effects of Croton genus, which is useful to the further research and development of this plant.

Key words: Croton genus, diterpenoids, chemical constituents, pharmacological effects

Shaochun Shi, Han Zhang, Shuangshuang Li, Qingbo Liu, Shaojiang Song. Review: diterpenoids from Croton genus (Euphorbiaceae) and their biological activity[J]. 亚洲传统医药.

Shaochun Shi, Han Zhang, Shuangshuang Li, Qingbo Liu, Shaojiang Song. Review: diterpenoids from Croton genus (Euphorbiaceae) and their biological activity[J]. Asina Journal Of Traditional Medicines.

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Review: diterpenoids from Croton genus (Euphorbiaceae) and their biological activity

Review: diterpenoids from Croton genus (Euphorbiaceae) and their biological activity

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