Isolation and characterization of lignans from the 
leaves of Isatis indigotica Fortune

亚洲传统医药 ›› 2020, Vol. 15 ›› Issue (3): 103-112.

• Regular Article • 上一篇下一篇

Isolation and characterization of lignans from the leaves of Isatis indigotica Fortune

Shuang Qiu, Peng Zhao, Yufei Xi, Xiaoxiao Huang*, Shaojiang Song*

Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China

收稿日期:2020-02-25 接受日期:2020-03-16 出版日期:2020-06-20 发布日期:2020-06-30

Isolation and characterization of lignans from the leaves of Isatis indigotica Fortune

Shuang Qiu, Peng Zhao, Yufei Xi, Xiaoxiao Huang*, Shaojiang Song*

Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China

Received:2020-02-25 Accepted:2020-03-16 Online:2020-06-20 Published:2020-06-30
Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-43520793 (Xiaoxiao Huang); +86-24-43520707 (Shaojiang Song); E-mail: xiaoxiao270@163.com (Xiaoxiao Huang); songsj99@163.com (Shaojiang Song). E-mail:xiaoxiao270@163.com; songsj99@163.com

摘要/Abstract

摘要： A phytochemical investigation of 80% EtOH exact of Isatis indigotica Fortune leaves yielded ten lignans (1–10), including six furofurans lignans (1–6), one arylnaphthalenes lignans (7) and three tetrahydrofurans lignans (8–10). Their structures were determined by HRESIMS spectroscopic data and extensive NMR analyses. Among them, compounds 6, 9 and 10 were isolated from the genus of Isatis for the first time.

关键词: Isatis indigotica, separation and purification, lignans, structural identification

Abstract: A phytochemical investigation of 80% EtOH exact of Isatis indigotica Fortune leaves yielded ten lignans (1–10), including six furofurans lignans (1–6), one arylnaphthalenes lignans (7) and three tetrahydrofurans lignans (8–10). Their structures were determined by HRESIMS spectroscopic data and extensive NMR analyses. Among them, compounds 6, 9 and 10 were isolated from the genus of Isatis for the first time.

Key words: Isatis indigotica, separation and purification, lignans, structural identification

Shuang Qiu, Peng Zhao, Yufei Xi, Xiaoxiao Huang, Shaojiang Song. Isolation and characterization of lignans from the leaves of Isatis indigotica Fortune[J]. 亚洲传统医药, 2020, 15(3): 103-112.

Shuang Qiu, Peng Zhao, Yufei Xi, Xiaoxiao Huang, Shaojiang Song. Isolation and characterization of lignans from the leaves of Isatis indigotica Fortune[J]. Asian Journal of Traditional Medicines, 2020, 15(3): 103-112.

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亚洲传统医药

Isolation and characterization of lignans from the leaves of Isatis indigotica Fortune

Isolation and characterization of lignans from the leaves of Isatis indigotica Fortune

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