亚洲传统医药 ›› 2021, Vol. 16 ›› Issue (1): 24-31.

• Regular Article • 上一篇    下一篇

Isolation and identification of chemical constituents of Pithecellobium clypearia (Jack.) Benth

Wanyi Shi, Yuxi Wang, Xiaoxiao Huang*   

  1. Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
  • 收稿日期:2020-03-22 接受日期:2020-06-02 出版日期:2021-02-20 发布日期:2021-03-02

Isolation and identification of chemical constituents of Pithecellobium clypearia (Jack.) Benth

Wanyi Shi, Yuxi Wang, Xiaoxiao Huang*   

  1. Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2020-03-22 Accepted:2020-06-02 Online:2021-02-20 Published:2021-03-02
  • Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-43520793; E-mail: xiaoxiao270@163.com. E-mail:xiaoxiao270@163.com

摘要: The twigs and leaves of Pithecellobium clypearia (Jack.) Benth are used as common Chinese traditional herbal medicine to treat upper respiratory tract infection, acute gastroenteritis and bacterial dysentery. The study isolated nine compounds from the EtOAc extract, all of which were obtained from Pithecellobium Mart. for the first time. Based on 1 H-NMR and 13C-NMR data, the structures of these compounds, including two ladiosiplodins and two dihydroisocoumarins, were elucidated.

关键词: Pithecellobium clypearia (Jack.) Benth, ladiosiplodins, dihydroisocoumarins

Abstract: The twigs and leaves of Pithecellobium clypearia (Jack.) Benth are used as common Chinese traditional herbal medicine to treat upper respiratory tract infection, acute gastroenteritis and bacterial dysentery. The study isolated nine compounds from the EtOAc extract, all of which were obtained from Pithecellobium Mart. for the first time. Based on 1 H-NMR and 13C-NMR data, the structures of these compounds, including two ladiosiplodins and two dihydroisocoumarins, were elucidated.

Key words: Pithecellobium clypearia (Jack.) Benth, ladiosiplodins, dihydroisocoumarins