亚洲传统医药 ›› 2021, Vol. 16 ›› Issue (4): 210-215.

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Colletodiphenol A, a new phenol derivative isolated from the endophytic fungus Colletotrichum capsici

  

  • 出版日期:2021-08-25 发布日期:2021-09-02

Colletodiphenol A, a new phenol derivative isolated from the endophytic fungus Colletotrichum capsici

  • Online:2021-08-25 Published:2021-09-02

摘要: A new C6-C2 dimer phenol derivative, colletodiphenol A (1), along with two known C6-C2 phenol derivatives (2,3) were isolated from the endophytic fungus Colletotrichum capsici related to the traditional Chinese medicine Paeonia lactiflora. Their structures were elucidated based on extensive spectroscopic data analysis, including HRESIMS, UV, IR, 1D and 2D NMR. The antioxidant and anti-inflammatory activities of the isolated compounds were evaluated, but none of them displayed significant activity.

关键词: Endophytic fungi, Colletotrichum capsici, Paeonia lactiflora Pall., phenols, secondary metabolites

Abstract: A new C6-C2 dimer phenol derivative, colletodiphenol A (1), along with two known C6-C2 phenol derivatives (2,3) were isolated from the endophytic fungus Colletotrichum capsici related to the traditional Chinese medicine Paeonia lactiflora. Their structures were elucidated based on extensive spectroscopic data analysis, including HRESIMS, UV, IR, 1D and 2D NMR. The antioxidant and anti-inflammatory activities of the isolated compounds were evaluated, but none of them displayed significant activity.

Key words: Endophytic fungi, Colletotrichum capsici, Paeonia lactiflora Pall., phenols, secondary metabolites