Please wait a minute...

本期目录

    2023年, 第18卷, 第5期 刊出日期:2023-10-30 上一期   
    Computational investigation on the molecular structure and chemical reactivity of a traditional Chinese medicine extract MK-1 molecule
    Jian Zhang
    2023 (5):  209-217. 
    摘要 ( 55 )   PDF(2925KB) ( 92 )  

    MK-1 molecule (C 16 H 16 O 2 ), the simplest structure of vitamin K (VK) compound family, is an extract from traditional Chinese medicine Cymbopogon distans (Nees ex Steud.) Wats (Chinese name YunXiangCao), which has attracted a great deal of attention in recent years due to its antiasthmatic, antitussives and expectorant effects. To investigate the molecular structure and chemical reactivity of MK-1 molecule, computational investigations on six conformational minima structures were carried out at the MP2/6-311++G(2d,2p) level of theory. Several local reactivity descriptors including condensed Fukui function, average local ionization energy, and molecular electrostatic potential on each individual atom were determined to predict the intrinsic reactivity of MK-1 molecule.



    相关文章 | 计量指标
    Research progress on chemical constituents and pharmacological effects of medicinal plant Gynostemma pentaphyllum
    Yibo Wang, Yi’an Shi, Guanyi Zhao, Shuo Wang, Ying Li, Yu Chen
    2023 (5):  218-235. 
    摘要 ( 56 )   PDF(4538KB) ( 75 )  

    Gynostemma pentaphyllum (G. pentaphyllum) is a traditional medicinal plant with medicinal and economic value. With in-depth research on the chemical compositions and pharmacological effects, the applications of G. pentaphyllum have been expanded. G. pentaphyllum has the effects of clearing heat and detoxification, relieving cough and phlegm, nourishing heart, tranquilizing nerves, and can be used to treat gastroenteritis, tracheitis, pharyngitis, hyperlipidemia, and arteriosclerosis. It can also be used to alleviate symptoms such as migraines, insufficient sleep, and white hair. In recent years, G. pentaphyllum has also been used for clinical adjuvant treatment of various cancers. In this study, the chemical constituents and pharmacological effects on G. pentaphyllum in recent years were reviewed. This review could provide reference for further development and utilization of G. pentaphyllum.

    相关文章 | 计量指标
    Investigation on vascular plant resources and their diversity in Wuzhishan, China
    Peiying Chen, Minli Ruan, Anhua Wang, Jingming Jia
    2023 (5):  236-245. 
    摘要 ( 49 )   PDF(1278KB) ( 34 )  
    Wuzhishan, located in the central part of Hainan Island and characterized by undulating terrain and diverse vegetation, is rich in plants. In October 2020, field investigations were carried out by the 14th Shenyang Pharmaceutical University Chinese Medicine Resources Scientific Expedition Team. Through specimen collection and literature retrieval, the team collected and analyzed vascular plants, resulting in the identification of 455 species belonging to 328 genera in 145 families. The dominant families are Leguminosae, Malvaceae, Compositae, Rubiaceae, Lauraceae, Pteridaceae, and Polypodiaceae. The main dominant species were perennial herb, comprising 147 species, 32.31% of the total. From the 367 species of medicinal vascular plants, the team screened and recorded 20 species of Li medicine according to indications of the medicinal use and the part of the plant used. As a result, the dominant families of vascular plants were similar to medicinal vascular plants, which means vascular plants is an important medicinal resource in Wuzhishan. Based on the investigation and research, further suggestions were made to strengthen the conservation and utilization of plant resources in Wuzhishan.
    相关文章 | 计量指标