亚洲传统医药

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2012年, 第7卷, 第4期　刊出日期：2012-08-20 上一期    下一期

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Pharmaceutical - analytic study of the Ayurvedic purification of Manahshila (realgar) Naveena Kodlady *;Doddamani MS;Patgiri BJ 2012 (4):  143-150.  摘要 ( 2645 )   Manahshila (realgar, arsenic disulphide) has been used in Ayurvedic medicine since ancient times for the treatment of conditions such as skin diseases, cough, asthma, certain eye diseases, and psychological disorders etc. Shodhana (purification) is an integral part of Ayurvedic processing especially for poisonous substances before they can be used for therapeutic purposes. In the case of Manahshila, which contains the heavy metal arsenic, it is advised that it should be purified optionally by carrying out seven levigations (Bhavana) of Zingiber officinalis Roscoe. (Ardraka) juice. A Shodhana of Manahshila was carried out and both Ashodhita Manahshila (AM – unpurified realgar) and Ardraka Shodhita Manahshila (ASM – realgar purified with ginger juice) were investigated by examination of the relevant physico – chemical parameters, quantitative elemental analysis, including the percentage of arsenic using atomic absorption spectrometry, particle size analysis using laser diffraction, and identification of chemical moieties using X – ray diffraction. A significant change was found in the particle size distribution where 50% of the AM particles were found to be 54.18 µm. while the figure for ASM was 15.55 µm. There was no change in the chemical composition and both AM and ASM remained as arsenic disulphide. 相关文章 | 计量指标

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Wound healing efficacy of a polyherbal ointment used to treat incisions, excisions and burn wounds in albino rats Elakiya Ponnusamy ;Jothi Gnanasekaran *;Radhika Jeyaraman 2012 (4):  151-158.  摘要 ( 962 )   The present study was carried out to evaluate the wound healing efficacy of a herbal ointment formulated with Madhuca indica L., Ziziphus mauritiana Lam., Calendula officinalis Linn. and Moringa pterygosperma Gaertn. embedded in an ointment base and used to treat incisions, excisions and burn wounds in an albino rat model. The rats were Wistar strain weighing 150-200 g which were divided into 9 groups each of 6 rats. Groups I, IV and VII served as wounded controls, Groups II, V and VIII were wounded and treated with Polyherbal Ointment (PHO) topically. The wound healing effect was evaluated in comparison with a reference ointment Soframycin, for excisions (Group III) and incisions (Group VI) and Burnol (Group IX) for burn wounds. The Polyherbal ointment (PHO) treated group showed a faster rate of wound contraction compared with the control groups. Topical application of the Polyherbal ointment in treated groups produced a significant increase (P<0.05) in wound breaking strength, hydroxyproline, hexosamine, protein, DNA, RNA and Superoxide Dismutase (SOD) levels. It also significantly reduced the level of Lipid peroxide (LPO) when compared with the control groups. Histological studies of the tissue from the PHO treated group showed increased and well organized bands of collagen, more fibroblasts and fewer inflammatory cells when compared with the control groups. These results strongly support the belief that the Polyherbal ointment (PHO) has antioxidant properties which may be responsible for and promote faster wound healing in rats at an effective topical dosage. Hence PHO is an economical option for wound treatment. 相关文章 | 计量指标

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A comparative study of isolated flavonoid and different extracts of Caesalpinia pulcherrima (L) Sw. for in vitro immunomodulatory effects on human neutrophils Smita Daniel Madagundi *;Manjunath Karibassapa Pawadshetter;Hasan Pasha Sholapur;Prasanna Habbu;Siddaruda Malleshappa Biradar 2012 (4):  159-167.  摘要 ( 918 )   1. Department of Pharmacognosy and Phytochemistry, SET’s College of Pharmacy, Dharwad 580002, Karnataka, India 2. Department of Pharmacognosy, KLES’s College of Pharmacy, Vidyanagar, Hubli-31, Karnataka, India 3. Department of Pharmacology, SET’s College of Pharmacy, Dharwad 580002, Karnataka, India 相关文章 | 计量指标

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Phytochemical, safety and pharmacokinetic profile of Jawarish-e-Bisbasa: a potent unani medicine for gastric disorders Sunita Shailajan *;Sasikumar Menon;Neelam Sayed;Harshvardhan Joshi;Bhavesh Tiwari 2012 (4):  168-177.  摘要 ( 903 )   Jawarish-e-Bisbasa, an Unani polyherbal formulation, is used traditionally in the clinical treatment of stomach ulcers, weakness of digestion, piles, flatulence, nausea, gastritis and as an energy enhancer for stomach. In the current work; phytochemical, safety and pharmacokinetic profile of Jawarish-e-Bisbasa has been evaluated. Phytochemical constituents in Jawarish-e-Bisbasa were qualitatively evaluated using standard tests. Safety of the formulation was affirmed by conducting acute oral toxicity in mice. Chemical characterization was carried out on the basis of piperine content. A simple HPLC method was developed for determination of piperine in rabbit plasma and applied to study the pharmacokinetics of piperine after oral administration of aqueous slurry of Jawarish-e-Bisbasa in rabbits. Jawarish-e-Bisbasa showed the presence of flavonoids, essential oils, tannins, glycosides, alkaloids and resins. It did not show any evident toxicity in mice. Piperine content in Jawarish-e-Bisbasa was 0.15±0.004 mg/g using HPLC. Piperine was detected in rabbit plasma with Cmax and Tmax of 79.21±1.24 ng/ml and 0.75±0.00 h respectively post administration of Jawarish-e-Bisbasa. The current work demonstrates a modern approach towards standardization of traditional Unani formulation Jawarish-e-Bisbasa. 相关文章 | 计量指标

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Traditional medicinal plants curing diabetes: A promise for today and tomorrow Sunil Kumar *;Meenu Saini;Vipin Kumar;Om Prakash;Renu Arya;Monika Rana; Dinesh Kumar 2012 (4):  178-188.  摘要 ( 1059 )   Even from early civilization, plants have been considered to be powerful tool in treating illness. The present article is an attempt to highlight the list of the traditional plants used to cure diabetes. Active constituents of any medicinal plant define the efficacy and safety of treatment to control diabetes. The herbal drugs with anti-diabetic activity are yet to be commercially formulated as modern medicines, even though they have been acclaimed for their therapeutic properties in the traditional systems of medicine. 相关文章 | 计量指标