›› 2008, Vol. 3 ›› Issue (5): 193-198.

• 论文 • Previous Articles     Next Articles

Studies on the chemical constituents of the vines of Streptocaulon juventas (Lour.) Merr.

Zhihui Liu; Songbo Li; Na Han; Dongxue Sun; Yunfeng Cao; Jun Yin *   

  1. School of Traditional Chinese Meteria Medica, Shenyang Pharmaceutical University, Shenyang
  • Received:2008-06-10 Revised:2008-10-15 Online:2008-10-15 Published:2008-10-15
  • Contact: Jun Yin

Abstract: The aqueous extract of the vines of Streptocaulon juventas was divided into four fractions following adsorption resin chromatography. Among them, the 30% fraction exhibited the strongest antiproliferate activity against human HL-60 leukemia cell lines. The chemical constituents of this fraction were investigated. Nine compounds were isolated by column chromatography and recrystallization. Their structures were identified as syringaldehyde (1), isofraxidin (2), ferulic acid (3), β -sitosterol (4), scopoletin (5), syringic acid (6), salicylaldehyde (7), scoparone (8), and daucosterol (9). Except for β-sitosterol and daucosterol, the other compounds were obtained from the genus for the first time.

Key words: Streptocaulon juventas, Asclepiadaceae, human HL-60 leukemia cell line, vines

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