›› 2011, Vol. 6 ›› Issue (4): 145-153.

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Estimation of antioxidant activity of microwave assisted extraction of total phenolics and flavonoids contents of the fruit Spondias mangifera Willd.

Muhammad Arif *; Sheeba Fareed; Md. Sarfaraj Hussain   

  1. Faculty of Pharmacy, Integral University, Kursi-road, Lucknow-226026, Uttar Pradesh. India
  • Received:2010-11-12 Revised:2011-05-06 Online:2011-08-20 Published:2011-08-20
  • Contact: Muhammad Arif

Abstract: The plant Spondias mangifera Willd, (Anacardiaceae), has been traditionally used for the treatment of inflammatory rheumatic pain, dysentery, diarrhoea, biliousness and as aromatic astringent, and refrigerant. The hardening of the endocarp of the fruit during development and maturation makes most of the fruit parts hard and tough. So, microwave irradiation was used to prepare an aqueous extract. In the present investigation, an attempt was made to extract the constituents of S. mangifera fruit and investigate them for antioxidant activity, reducing power, and the content of total phenolics, total flavonoids, DPPH, nitric oxide and peroxide radicals. The results obtained in the study indicate that S. mangifera fruit is a potential source of natural antioxidants. All the activities were found to be concentration dependent and increased when increasing amounts of sample were used. Flavonoids, phenolic compounds like tannins, and terpenoids may be responsible for the antioxidant activity of this plant fruit. Microwave extraction of the plant fruit is a good alternative to conventional extraction methods. Microwave extraction of the plant fruit was a successful method for extraction of the toconstituents.

Key words: Indian hog plum, Spondias mangifera Willd, phenolics, flavonoids, antioxidant activity, microwave assisted extraction

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