›› 2011, Vol. 6 ›› Issue (6): 252-258.

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Phytochemical and antibacterial properties of Rhododendron campanulatum from Nepal

Atmika Paudel 1,2 *; Suresh Panthee 1,3; Sushma Shakya 1,4; Sadhana Amatya 1; Tirtha Maiya Shrestha 1; Mohan Prasad Amatya 1
  

  1. 1. Department of Pharmacy and Pharmacology, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal 2. Department of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan 3. Department of Biomedical Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan 4. Department of Drug Administration, Nepal Government, Kathmandu,Madan Bhandari Path-4, Nepal
  • Received:2011-02-24 Revised:2011-10-08 Online:2011-12-20 Published:2011-12-20
  • Contact: Atmika Paudel

Abstract: Phytochemical and antibacterial studies were performed with the extracts of Rhododendern campanulatum. The phytochemical studies showed the presence of terpenoids in the petroleum and methanol extracts, steroids in the diethyl ether and chloroform extracts, tannins in the diethyl ether and methanol extracts, and glycosides, flavonoids, and saponins in the methanol extract. The diethyl ether and methanol extracts exhibited dose-dependent antimicrobial activity against Staphylococcus aureus and Streptococcus faecalis while no activity was observed against Gram-negative bacteria. These results suggest that R. campanulatum is a potential source of antibacterial agents.

Key words: phytochemical, antibacterial, Rhododendron campanulatum, Gram positive, cup diffussion

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