Asina Journal Of Traditional Medicines

Previous Articles     Next Articles

Main chemical constituents and pharmacological properties of Harrisonia perforata (Blanco) Merr.

Shifang Li, Zhiyang Yan, Xiaoxiao Huang 1,2 *, Shaojiang Song 1 *   

  1. 1 Department of Natural Product Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, China; 2 Chinese People's Liberation Army 210 Hospital, Dalian 116021, People’s Republic of China
  • Received:2017-10-23 Revised:2017-12-30 Online:2018-02-20 Published:2018-04-03
  • Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-23986486 (Xiaoxiao Huang); E-mail: xiaoxiao270@163.com (Xiaoxiao Huang), songsj99@163.com (Shaojiang Song).

Abstract: Harrisonia perforata (Blanco) Merr. is a bitter shrub throughout southeast of Asia, belonging to the Harrisonia genus of Simarubaceae family. Its roots, stems, leaves and branches had been utilized as a folk medicine to treat cancer, malaria and wound healing. Previous researches indicated that H. perforata mainly contains limonoids, prenylated polyketides and chromones, which possessed a spectrum of biological activities. This paper summarized the primary chemical constitutions and pharmacological activities of H. perforata for the follow-up study of this plant.

Key words: Harrisonia perforata (Blanco) Merr., chemical constituents, pharmacological activities, review