Antimicrobial activities and analysis of the crude extract,
fractions and compounds from the Lomatogonium rotatum

Asian Journal of Traditional Medicines ›› 2020, Vol. 15 ›› Issue (4): 145-152.

Antimicrobial activities and analysis of the crude extract, fractions and compounds from the Lomatogonium rotatum

Ruoning Wang, Qin He, Qingdi Mu, Mengyuan Tan, Jing Wang, Chongning Lv, Hang He, Jincai Lu, Lingyun Jia*

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Box 79, Shenyang 110016, Liaoning Province, PR China

Received:2020-02-18 Accepted:2020-03-16 Online:2020-08-20 Published:2020-09-01
Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Box 79, Wenhua Road 103, Shenhe District, Shenyang 110016, Liaoning Province, PR China; Tel.: +86-24-43520729; E-mail: jialingyun2003@126.com. E-mail:jialingyun2003@126.com

Abstract

Abstract: This study was evaluated the antimicrobial activities of the crude extract, different fractions, and compounds from the plant of Lomatogonium carinthiacum. The fractions of chloroform and compounds 5, 2 and 6 exhibited stronger antimicrobial activities. Compound 5 was the most active while Staphylococcus aureus and Candida albicans were sensitive to all the tested compounds. The existence of a relationship between the xanthone structures and inhibition of microorganism activity. The antimicrobial activity of this plant was reported here firstly. The results provided evidence that the studied plant extract, fractions as well as some of the isolated compounds might be potential sources of new antimicrobial drug.

Key words: Lomatogonium carinthiacum, fractions, compounds, antimicrobial activities, HPLC-EIS-MS/MS

Ruoning Wang, Qin He, Qingdi Mu, Mengyuan Tan, Jing Wang, Chongning Lv, Hang He, Jincai Lu, Lingyun Jia. Antimicrobial activities and analysis of the crude extract, fractions and compounds from the Lomatogonium rotatum[J]. Asian Journal of Traditional Medicines, 2020, 15(4): 145-152.

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Asian Journal
Of Traditional Medicines