Physicochemical properties and antioxidant activities of
polysaccharides extracted from Panax ginseng C. A. Meyer with
graded percipitation method

Asian Journal of Traditional Medicines ›› 2020, Vol. 15 ›› Issue (6): 309-319.

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Physicochemical properties and antioxidant activities of polysaccharides extracted from Panax ginseng C. A. Meyer with graded percipitation method

Xinying Wang 1, Yue Lin 1, Jia Liu 1, Zhaojun Wang 1, Linlin Liu 1, Yingling Wang 1, Jincai Lu 1,2*

1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China; 2. Liaoning Provincial Key Laboratory of TCM Resources Conservation and Development, Shenyang Pharmaceutical University, Shenyang 110006, PR China

Received:2020-07-02 Accepted:2020-09-13 Online:2020-12-20 Published:2020-12-23
Contact: Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016, PR China; Tel. (Fax): +86-24-43520728; E-mail: jincailu@126.com. E-mail:jincailu@126.com

Abstract

Abstract: Ginseng polysaccharides were extracted by water decoction from Panax ginseng C. A. Meyer (Cultivated Ginseng), named CGPS. Four polysaccharide fractions, CGPS-20, CGPS-40, CGPS-60 and CGPS-80, were precipitated at final ethanol concentrations of 20%, 40%, 60% and 80%, respectively. Physicochemical properties, molecular weight, monosaccharide composition and antioxidant capacity of polysaccharide fractions were all investigated. The results indicated that changing the concentration of ethanol could precipitate polysaccharides into fractions with different molecular weights, functional group composition and physicochemical properties, eventually leading to differences in antioxidant activity, which would help to find a simple, efficient, and reliable method for rapid extraction and purification of antioxidant polysaccharides from Panax ginseng C. A. Meyer. Among the four polysaccharide fractions, CGPS-80 had lower molecular weight, higher contents of uronic acid and total phenolic, and stronger scavenging ability on DPPH∙ and ABTS∙+ radicals.

Key words: Ginseng polysaccharides, graded ethanol precipitation, physicochemical property, antioxidant activity

Xinying Wang, Yue Lin, Jia Liu, Zhaojun Wang, Linlin Liu, Yingling Wang, Jincai Lu. Physicochemical properties and antioxidant activities of polysaccharides extracted from Panax ginseng C. A. Meyer with graded percipitation method[J]. Asian Journal of Traditional Medicines, 2020, 15(6): 309-319.

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Asian Journal
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Physicochemical properties and antioxidant activities of polysaccharides extracted from Panax ginseng C. A. Meyer with graded percipitation method

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Physicochemical properties and antioxidant activities of polysaccharides extracted from Panax ginseng C. A. Meyer with graded percipitation method

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