Asian Journal of Traditional Medicines ›› 2020, Vol. 15 ›› Issue (6): 360-374.

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Research progress on chemical constituents in Periploca forrestii and their pharmacological activities

Shuang Qiu, Peng Zhao, Xiaoxiao Huang*, Shaojiang Song*   

  1. Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2020-03-13 Accepted:2020-06-30 Online:2020-12-20 Published:2020-12-23
  • Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-43520793 (Xiaoxiao Huang); +86-24-43520707 (Shaojiang Song); E-mail: xiaoxiao270@163.com (Xiaoxiao Huang); songsj99@163.com (Shaojiang Song). E-mail:xiaoxiao270@163.com;songsj99@163.com

Abstract: Periploca forrestii Schltr. belonging to the family of Apocynaceae, is one of the “three treasures of Miao medicine”, which was utilized by the Miao people in China for the treatment of rheumatoid arthritis, fractures and wound. Phytochemical investigations have discovered that the main constituents of Periploca forrestii were steroids, terpenoids, flavonoids and their glycosides, flavanols, quinones and phenylpropanoids. Modern pharmacological studies have shown that it possesses a wide range of biological activities, such as anti-inflammatory, anti-rheumatoid arthritis, anticancer, immunosuppressive, neuroprotective and other properties. This paper summarized the primary chemical constituents and pharmacological effects of Periploca forrestii, hoping to provide a reference for its further development and utilization.

Key words: Periploca forrestii Schltr., chemical constituents, pharmacological activities, review

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