Research progress on chemical constituents in Sigesbeckiae Herba and their pharmacological activities

Abstract

Abstract: Sigesbeckiae Herba, a dry whole plant of Sigesbeckia glabrescens Makino, Sigesbeckia pubescens Makino and Sigesbeckia orientalis L., is a traditional Chinese medicine used to dispel dampness, dredge meridians and collaterals, clear heat and detoxicate. Its chemical components are complex and abundant, including mainly diterpenoids, sesquiterpenoids and flavonoids. Among them, diterpenoids are the main active components. Modern pharmacological studies have found that the compounds isolated from Sigesbeckiae Herba have anti-inflammatory, anti-tumor, antithrombus and other pharmacological activities. This review systematically summarized the chemical components identified from Sigesbeckiae Herba and their pharmacological activities by searching Chinese and English databases, in order to provide references for the further development of Sigesbeckiae
Herba and the improvement of its quality standards.

Key words: Sigesbeckiae Herba, Sigesbeckia glabrescens Makino, Sigesbeckia pubescens Makino, Sigesbeckia orientalis L., chemical constituents, pharmacological activities

Meiya Lian, Xiaoxu Gao, Jingming Jia, Anhua Wang. Research progress on chemical constituents in Sigesbeckiae Herba and their pharmacological activities[J]. Asian Journal of Traditional Medicines, 2021, 16(3): 161-184.

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