Asian Journal of Traditional Medicines ›› 2021, Vol. 16 ›› Issue (4): 234-239.

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Network pharmacology-based virtual screening of active alkaloid ingredients from Piper nigrum L. and the potential targets against Parkinson’s disease

  

  • Online:2021-08-25 Published:2021-09-02

Abstract: Parkinson’s disease (PD) is a common neurodegenerative disease. Despite a great deal of research on this disease, there is still no definitive treatment plan. Literature investigations have shown that Piper nigrum L. has a protective effect on the nerve center. Therefore, network pharmacology was used in this study to investigate the therapeutic potential of P. nigrum for PD. As a result, six active alkaloid ingredients and four potential targets were obtained. This study laid the foundation for finding the lead compounds from P. nigrum to treat PD.

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