亚洲传统医药
亚洲传统医药

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›› 2015, Vol. 10 ›› Issue (6): 129-133.

• 论文 • 上一篇    下一篇

Research on the biotransformation of fourschisandra lignans

Zehai Song, Ye Houa, Na Han, Zhihui Liu, Jun Yin*   

  1. Development and Utilization Key Laboratory of Northeast Plant Materials, School ofTraditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang,110016, China
  • 收稿日期:2014-06-03 修回日期:2015-10-19 出版日期:2015-12-20 发布日期:2015-12-20

Research on the biotransformation of fourschisandra lignans

Zehai Song, Ye Houa, Na Han, Zhihui Liu, Jun Yin*   

  1. Development and Utilization Key Laboratory of Northeast Plant Materials, School ofTraditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang,110016, China
  • Received:2014-06-03 Revised:2015-10-19 Online:2015-12-20 Published:2015-12-20
  • Contact: Jun Yin

摘要： The biotransformation of deoxyschisandrin (1) was investigated using Mucor polymorphosporus Pispek AS 3.3443. A series
of products were identified as schisandrin (2), 7(18)-dehydroschisandro A (3), iso-schisandrin (4), (-)-gomisin K1 (5). These
microbial metabolites can be used as important standard samples in the research of metabolism.

Abstract: The biotransformation of deoxyschisandrin (1) was investigated using Mucor polymorphosporus Pispek AS 3.3443. A series
of products were identified as schisandrin (2), 7(18)-dehydroschisandro A (3), iso-schisandrin (4), (-)-gomisin K1 (5). These
microbial metabolites can be used as important standard samples in the research of metabolism.

Key words: schisandra lignans, deoxyschisandrin, biotransformation, metabolism

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