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›› 2012, Vol. 7 ›› Issue (2): 87-95.
• Regular Articles • 上一篇
Arumugam Vimalavady 1, Kadavul Krishnan 1, Arumugame Chanemougame Tangavelou 2
Arumugam Vimalavady 1, Kadavul Krishnan 1, Arumugame Chanemougame Tangavelou 2
摘要： An ethnomedicinal plant, Hugonia mystax L., was examined for preliminary phytochemical screening, physiochemical parameters and antimicrobial activity. Preliminary phytochemical screening showed the presence of various classes of secondary metabolites such as flavonoids, phenols, saponins, steroids, tannins and terpenoids. Physico chemical parameters helps to identify the crude drugs from adulterants and the antimicrobial activity of petroleum ether, chloroform, ethanol and aqueous leaf extracts showed significant activity against the human pathogens such as Streptococcus pneumoniae causing brain abscesses, pneumonia and septic arthritis; Proteus vulgaris, Pseudomonas aeruginosa causing urinary tract infections and septicaemia; Salmonella typhi causing typhoid fever, Vibrio species causing diarrheal infections and the fungus Candida albicans causes urinary tract infections. The antimicrobial activity of the petroleum ether, chloroform, ethanol and aqueous leaf extracts showed concentration-dependent activity against all the tested bacteria at various concentrations. The determination of minimum inhibitory concentration (MIC) determination of minimum bactericidal concentrations (MBC) and minimum fungicidal concentrations (MFC) were carried out. Thus the present findings revealed the medicinal potential of H. mystax to develop a drug against various human ailments.
