亚洲传统医药 ›› 2020, Vol. 15 ›› Issue (2): 55-64.

• Regular Article • 上一篇    下一篇

Aromatic compounds from Solanum nigrum L. and their antioxidant activities

Wei Xu, Ming Bai, Xiaoxiao Huang*   

  1. Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
  • 收稿日期:2020-02-24 接受日期:2020-03-16 出版日期:2020-04-20 发布日期:2020-04-30

Aromatic compounds from Solanum nigrum L. and their antioxidant activities

Wei Xu, Ming Bai, Xiaoxiao Huang*   

  1. Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2020-02-24 Accepted:2020-03-16 Online:2020-04-20 Published:2020-04-30
  • Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Rd., Shenyang 110016, China; Tel.: +86-24-43520793; E-mail: xiaoxiao270@163.com. E-mail:xiaoxiao270@163.com

摘要: Solanum nigrum L., belonging to the genus Solanum of Solanaceae family, is widely distributed in temperate and tropical regions of the world. It possesses the effects of clearing away heat and detoxification. A wide spectrum of chemical constituents have been isolated from the Solanum nigrum L., including lignans, steroids, etc. The structures of the eight compounds were determined by comprehensive spectroscopic analyses. It is noteworthy that compounds 1–4, 6 and 8 have been isolated from Solanum nigrum L. for the first time. All compounds were evaluated for their antioxidant activities by ABTS and DPPH assays. Based on the results, Solanum nigrum L. could be used as a new natural antioxidant in biomedical applications.

关键词: Solanum nigrum L., Solanaceae family, aromatic compounds, antioxidant activity

Abstract: Solanum nigrum L., belonging to the genus Solanum of Solanaceae family, is widely distributed in temperate and tropical regions of the world. It possesses the effects of clearing away heat and detoxification. A wide spectrum of chemical constituents have been isolated from the Solanum nigrum L., including lignans, steroids, etc. The structures of the eight compounds were determined by comprehensive spectroscopic analyses. It is noteworthy that compounds 1–4, 6 and 8 have been isolated from Solanum nigrum L. for the first time. All compounds were evaluated for their antioxidant activities by ABTS and DPPH assays. Based on the results, Solanum nigrum L. could be used as a new natural antioxidant in biomedical applications.

Key words: Solanum nigrum L., Solanaceae family, aromatic compounds, antioxidant activity