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本期目录

    2019年, 第14卷, 第4期 刊出日期:2019-08-20 上一期   
    Regular Article
    Integrated evaluation of HPLC fingerprints for the quality control of Ginseng Yang Rong Wan by multi-wavelength fusion fingerprint method
    Hanxiao Chi, Guoxiang Sun
    2019 (4):  171-182. 
    摘要 ( 382 )   PDF(1736KB) ( 1332 )  
    The aim of this study was to develop comprehensive evaluation methods for the quality control of Ginseng Yang Rong Wan (RSYRW). Multi-wavelength fusion fingerprints were successfully developed by high-performance liquid chromatography, which avoided the one-sidedness of single fingerprinting. Characteristic fingerprints of thirty batches of samples were generated at five wavelengths and evaluated by quantified ratio fingerprint method (QRFM). The results showed that thirty batches of samples were classified into seven grades. The methods established in this paper were found suitable for the analysis of Ginseng Yang Rong Wan.
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    Network pharmacology-based prediction and verification of the molecular targets and pathways for Piper longum Linn. against liver cancer
    Liwei Lu, Jie Wang, Xiaoxiao Huang, Shaojiang Song
    2019 (4):  183-192. 
    摘要 ( 359 )   PDF(1227KB) ( 369 )  
    Liver cancer is a common malignant tumor, which is one of the most common causes of cancer related deaths worldwide, specially, in China. Piper longum Linn. is a traditional Chinese medicine that is used to treat and prevent diseases in clinical practice, however, the active ingredients and potential targets of its action against liver cancer remain unclear. In this study, network pharmacology approach was used to identify active ingredients and the major targets of Piper longum against liver cancer. In addition, the key pathways were also predicted on the network pharmacology level, which might be beneficial to the chemical basis and pharmacological studies of this plant.
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    Review
    The Peperomia dindygulensis: a review of phytochemistry and pharmacology perspectives
    Zhikang Duan, Yuxi Wang, Xiaoxiao Huang
    2019 (4):  193-201. 
    摘要 ( 326 )   PDF(1281KB) ( 403 )  
    Plant of peperomia dindygulensis Miq. is widely distributed in southern regions of China, which is traditionally used to treat cough, measles, abscesses and cancerous swelling in Chinese folk. As a traditional medicinal agent, a wide spectrum of chemical constituents have been isolated from the P. dindygulensis, including lignans, flavonoids, flavone glycosides, polyketides and other compounds. The research shows that these compounds exhibited bioactivities including antitumor and antiangiogenesis. Hence, this report is presented as a review centered on the chemical constituents and pharmacological activities of the P. dindygulensis, aiming at its further development and potential value.
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    Research review on the main chemical constituents and pharmacological effects of Elephantopus scaber L.
    Shuhui Dong, Ming Bai, Xiaoxiao Huang, Shaojiang Song
    2019 (4):  202-212. 
    摘要 ( 429 )   PDF(1724KB) ( 467 )  
    Elephantopus scaber L. belongs to Elephantopus plant of Compositae, is widely used as the common Chinese herbal medicine in folk. Phytochemical investigations of the E. scaber have resulted in the isolation of triterpennoids, sesquiterpene lactones, sesquiterpene phenols, steroids, flavones, anthraquinones, peptides, lipid compounds and aryl compounds. It possesses the effects of antibacterial, clearing away heat and detoxification, detumescence and diuresis, and is used for treating lung cancer, cervical cancer, liver cancer, nasopharyngeal cancer, breast cancer, anemia and diarrhea. The research progress in the chemical constituents of E. scaber and pharmacological effects are reviewed for better explore and utilize the E. scaber resource.
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