Activity of xanthones isolated from Lomatogonium rotatum

亚洲传统医药 ›› 2020, Vol. 15 ›› Issue (3): 113-120.

• Regular Article • 上一篇下一篇

Activity of xanthones isolated from Lomatogonium rotatum

Qingdi Mu, Qin He, Mengyuan Tan, Ruoning Wang, Jing Wang, Chongning Lv, Hang He, Jincai Lu, Lingyun Jia*

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Box 79, Shenyang 110016, Liaoning Province, PR China

收稿日期:2020-03-04 接受日期:2020-06-01 出版日期:2020-06-20 发布日期:2020-06-30

Activity of xanthones isolated from Lomatogonium rotatum

Qingdi Mu, Qin He, Mengyuan Tan, Ruoning Wang, Jing Wang, Chongning Lv, Hang He, Jincai Lu, Lingyun Jia*

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Box 79, Shenyang 110016, Liaoning Province, PR China

Received:2020-03-04 Accepted:2020-06-01 Online:2020-06-20 Published:2020-06-30
Contact: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Box 79, Wenhua Road 103, Shenhe District, Shenyang 110016, Liaoning Province, PR China; Tel.: +86-24-43520729; E-mail: jialingyun2003@126.com. E-mail:jialingyun2003@126.com

摘要/Abstract

摘要： Thirteen xanthones were isolated from L. rotatum, which were established as 1,8-dihydroxy-3,4,5-trimethoxyxanthone (1); 1-hydroxy-3,7,8-trimethoxyxanthone (2); 8-hydroxy-1,3,5-trimethoxyxanthone(3); 1-hydroxy-3,4,5-trimethoxyxanthone (4); 1-hydroxy-3,5,8-trimethoxyxanthone (5); 1,4,8-trihydroxy-5,6-dimethoxyxanthone (6); 1,3,8-trihydroxy-4,7-dimethoxyxanthone (7); 1,8-dihydroxy-3,7-dimethoxyxanthone (8); 1-hydroxy-3,5-dimethoxyxanthone (9); 1-hydroxy-2,3,4,5-tetramethoxyxanthone (10); 1-hydroxy-2,3,4,7-tetramethoxyxanthone (11); 1,7-dihydroxy-3,8-dimethoxyxanthone (12) ; rel-1,3,5,8-tetrahydroxy- 2,4,6,7-tetrahydroxanthen-9-one (13). Compounds 4, 6, 7, 9, 10, 11, 12 and 13 are reported for the first time from Lomatogonium. Furthermore, the activity of xanthones was assessed.

关键词: Lomatogonium rotatum, xanthones, activity

Abstract: Thirteen xanthones were isolated from L. rotatum, which were established as 1,8-dihydroxy-3,4,5-trimethoxyxanthone (1); 1-hydroxy-3,7,8-trimethoxyxanthone (2); 8-hydroxy-1,3,5-trimethoxyxanthone(3); 1-hydroxy-3,4,5-trimethoxyxanthone (4); 1-hydroxy-3,5,8-trimethoxyxanthone (5); 1,4,8-trihydroxy-5,6-dimethoxyxanthone (6); 1,3,8-trihydroxy-4,7-dimethoxyxanthone (7); 1,8-dihydroxy-3,7-dimethoxyxanthone (8); 1-hydroxy-3,5-dimethoxyxanthone (9); 1-hydroxy-2,3,4,5-tetramethoxyxanthone (10); 1-hydroxy-2,3,4,7-tetramethoxyxanthone (11); 1,7-dihydroxy-3,8-dimethoxyxanthone (12) ; rel-1,3,5,8-tetrahydroxy- 2,4,6,7-tetrahydroxanthen-9-one (13). Compounds 4, 6, 7, 9, 10, 11, 12 and 13 are reported for the first time from Lomatogonium. Furthermore, the activity of xanthones was assessed.

Key words: Lomatogonium rotatum, xanthones, activity

Qingdi Mu, Qin He, Mengyuan Tan, Ruoning Wang, Jing Wang, Chongning Lv, Hang He, Jincai Lu, Lingyun Jia. Activity of xanthones isolated from Lomatogonium rotatum[J]. 亚洲传统医药, 2020, 15(3): 113-120.

Qingdi Mu, Qin He, Mengyuan Tan, Ruoning Wang, Jing Wang, Chongning Lv, Hang He, Jincai Lu, Lingyun Jia.

Activity of xanthones isolated from Lomatogonium rotatum

[J]. Asian Journal of Traditional Medicines, 2020, 15(3): 113-120.

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Activity of xanthones isolated from Lomatogonium rotatum

Activity of xanthones isolated from Lomatogonium rotatum

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