亚洲传统医药

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2014年, 第9卷, 第4期　刊出日期：2014-08-20 上一期    下一期

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A study of the pseudo-aldosteronism toxicity oflicorice flavonoid dispersible tablets Jie Liu, Yuqiong Wang, Sanhu Gou, Jingman Ni 2014 (4):  88-97.  摘要 ( 444 )   PDF(966KB) ( 419 )   Licorice flavonoids are readily obtained from the traditional herbal medicine Glycyrrrhiza uralensis Fischer. In this study, the pseudo-aldosteronism toxicity of licorice flavonoid dispersible tablets (LFT) in male SD rats was evaluated. The serum concentrations of sodium, potassium and aldosterone were examined, and the blood pressure was measured on day 0, 14, and 21. The results obtained showed that rats fed LFT exhibited no statistically significant differences in serum sodium, potassium and aldosterone, and also systolic and diastolic blood pressure in comparison with the CON group. Furthermore, LFT caused no obvious damage to the heart, aortic vascular system and the kidneys. Therefore, our study shows that LFT did not produce pseudo-aldosteronism, induced by Glycyrrhizin and the herbal preparation. So, this study provides a good foundation for new studies involving the further application of LFT. 相关文章 | 计量指标

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Purification of an antibacterial effective fractionfrom Syringae Folium using macroporous resins Cuiting Wu, Ping Shao, Na Han, Zhihui Liu, Zhengyuan Zhou, Dezu Miao, Wei Li, Jun Yin 2014 (4):  98-104.  摘要 ( 272 )   PDF(616KB) ( 353 )   This paper is to investigate the purification of an antibacterial effective fraction from Syringae Folium using macroporous resins. Static adsorption and desorption tests were carried out for the screening of macroporous resins. A desorption experiment was performed on selected D101 resin to optimize the separation process. The effects of several parameters, including the elution flow rate, and ratio of the diameter to the height of the bed, were examined in an orthogonal experiment. The results obtained demonstrated that the optimized conditions, i.e. an elution solution of 55% ethanol, an absorption flow rate of 1 bed volume (BV) /h, an elution flow rate of 5 BV/h and etc. The content of the antibacterial effective component was over 65% after purification using D101 resin, indicating that the present method is suitable for the large-scale preparation of an antibacterial effective fraction from Syringae Folium. 相关文章 | 计量指标

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Investigating antimicrobial aspects of Acampepraemorsa (Roxb.) Blatt. & mc. Geeta Swami, Jyotsna Salvi, S. S. Katewa 2014 (4):  105-109.  摘要 ( 379 )   PDF(527KB) ( 466 )   The paper deals with screening of antimicrobial activity of leaves and root of Acampe praemorsa (Roxb.). The plant material was collected from the Phulwari-ki-Nal sanctuary of Southern Rajasthan. Results were compared with standard drug streptomycin. Petroleum ether extract of leaves showed significant activity against Escherichia coli (17.66±0.47 mm). Methanolic extract of fruit pulp and fruit rind of the plant showed good activity against all the bacteria tested and the zone of inhibition varied from 10.00 mm to 17.66 mm. Less encouraging activity of methanolic extract of leaf against Proteus mirabilis was reported. 相关文章 | 计量指标